Article
Excessive Myosin activity in mbs mutants causes photoreceptor movement out of the Drosophila eye disc epithelium.
Molecular biology of the cell - 1 Jul 2004
Lee Arnold, Treisman Jessica E
Abstract excerpt
Neuronal cells must extend a motile growth cone while maintaining the cell body in its original position. In migrating cells, myosin contraction provides the driving force that pulls the rear of the cell toward the leading edge. We have characterized the function of myosin light chain phosphatase, which down-regulates myosin activity, in Drosophila photoreceptor neurons. Mutations in the gene encoding the myosin...
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