Article
Growth control by a moving morphogen gradient during Drosophila eye development.
Development (Cambridge, England) - 1 May 2014
Wartlick Ortrud, Jülicher Frank, Gonzalez-Gaitan Marcos
Abstract excerpt
During morphogenesis, organs grow to stereotyped sizes, but growth control mechanisms are poorly understood. Here, we measured the signaling dynamics of the morphogen Dpp, one of several Drosophila factors controlling morphogenetic growth, in the developing eye. In this tissue, the Dpp expression domain advances from the posterior to the anterior tissue edge. In front of this moving morphogen source, signaling...
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