Article
Morphogenesis in Drosophila requires nonmuscle myosin heavy chain function.
Genes & development - 1 Jan 1993
Young P E, Richman A M, Ketchum A S, Kiehart D P
Abstract excerpt
We provide the first link between a known molecular motor and morphogenesis, the fundamental process of cell shape changes and movements that characterizes development throughout phylogeny. By reverse genetics, we generate mutations in the Drosophila conventional nonmuscle myosin (myosin II) heavy chain gene and show that this gene is essential. We demonstrate that these mutations are allelic to previously...
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