Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

FcgammaRIIa expression with FcgammaRI results in C-reactive protein- and IgG-mediated phagocytosis.

Journal of leukocyte biology - 1 Jun 2004

Bodman-Smith Katherine B, Gregory Rachel E, Harrison Patrick T, Raynes John G

Abstract excerpt

C-reactive protein (CRP) is a pattern-recognition molecule, which can bind to phosphorylcholine and certain phosphorylated carbohydrates found on the surface of a number of microorganisms. CRP has been shown recently to bind human Fc receptor for immunoglobulin G (IgG; FcgammaR)I and mediate phagocytosis and signaling through the gamma-chain. To date, binding of monomeric CRP to FcgammaRII has been contentious....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to C-Reactive Protein
Share to Erythrocytes
Share to Immunoglobulin Fab Fragments

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunoglobulin G

Share to Phagocytosis

Share to Receptors, IgG

Share to Tyrosine

Source

Identifiers

PMID: 15075346
DOI: 10.1189/jlb.0703306

Genes

CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FcgammaRIIa expression with FcgammaRI results in C-reactive protein- and IgG-mediated phagocytosis.PMID 15075346Read ↗

C-reactive protein increases cytokine responses to Streptococcus pneumoniae through interactions with Fc gamma receptors.Semantic proximity Read ↗

Recognition and functional activation of the human IgA receptor (FcalphaRI) by C-reactive protein.Semantic proximity Read ↗

C-reactive protein binding to FcgammaRIIa on human monocytes and neutrophils is allele-specific.Semantic proximity Read ↗

Molecular dissection of Fc gamma receptor-mediated phagocytosis.Semantic proximity Read ↗

Fcgamma receptor transmembrane domains: role in cell surface expression, gamma chain interaction, and phagocytosis.Semantic proximity Read ↗

Human Fcγ-receptors selectively respond to C-reactive protein (CRP) isoformsSemantic proximity Read ↗

The Fcgamma receptor IIA-R/R131 genotype is associated with severe sepsis in community-acquired pneumonia.Semantic proximity Read ↗

Monomeric CRP contributes to complement control in fluid phase and on cellular surfaces and increases phagocytosis by recruiting factor H.Semantic proximity Read ↗

Two distinct regions of FC gamma RI initiate separate signalling pathways involved in endocytosis and phagocytosis.Semantic proximity Read ↗

Analysis of binding sites in human C-reactive protein for Fc{gamma}RI, Fc{gamma}RIIA, and C1q by site-directed mutagenesis.Semantic proximity Read ↗

Protection from Streptococcus pneumoniae infection by C-reactive protein and natural antibody requires complement but not Fc gamma receptors.Semantic proximity Read ↗

FcgammaRIIA polymorphisms in Streptococcus pneumoniae infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.