Article
Molecular and cellular analysis of the pH response transcription factor PacC in the fungal symbiont Epichloë festucae.
Fungal genetics and biology : FG & B - 1 Dec 2015
Lukito Yonathan, Chujo Tetsuya, Scott Barry
Abstract excerpt
In order to survive and adapt to the environment, it is imperative for fungi to be able to sense and respond to changes in extracellular pH conditions. In ascomycetes, sensing of extracellular pH is mediated by the Pal pathway resulting in activation of the PacC transcription factor at alkaline pH. The role of PacC in regulating fungal virulence and pathogenicity has been described in several pathogenic fungi but...
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