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Article

Involvement of S-adenosylmethionine in G1 cell-cycle regulation in Saccharomyces cerevisiae.

Proceedings of the National Academy of Sciences of the United States of America - 20 Apr 2004

Mizunuma Masaki, Miyamura Kazunori, Hirata Dai, Yokoyama Hiroshi, Miyakawa Tokichi

Abstract excerpt

S-adenosyl-l-methionine (AdoMet) is a molecule central to general metabolism, serving as a principal methyl donor for methylation of various cellular constituents. The alteration in the availability of AdoMet has profound effect on cell growth. A mutant allele of Saccharomyces cerevisiae gene SAH1 encoding S-adenosyl-l-homocysteine (AdoHcy) hydrolase, was isolated as a mutation that suppressed the...

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Identifiers

PMID: 15073333
DOI: 10.1073/pnas.0308314101
PMCID: PMC395927

Genes

MET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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