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A new method for isolation of S-adenosylmethionine (SAM)-accumulating yeast.

Applied microbiology and biotechnology - 1 Feb 2006

Shobayashi Megumi, Mukai Nobuhiko, Iwashita Kazuhiro, Hiraga Yoshikazu, Iefuji Haruyuki

Abstract excerpt

S-Adenosylmethionine (SAM) is an important metabolite that participates in many reactions as a methyl group donor in all organisms, and has attracted much interest in clinical research because of its potential to improve many diseases, such as depression, liver disease, and osteoarthritis. Because of these potential applications, a more efficient means is needed to produce SAM. Accordingly, we developed a...

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Antifungal Agents
Drug Resistance, Fungal
Ergosterol
Gas Chromatography-Mass Spectrometry
Magnetic Resonance Spectroscopy

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Oxidoreductases

S-Adenosylmethionine

Saccharomyces cerevisiae Proteins

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PMID: 16010571
DOI: 10.1007/s00253-005-0009-7

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