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Article

The role of the Shigella flexneri yihE gene in LPS synthesis and virulence.

Microbiology (Reading, England) - 1 Apr 2004

Edwards-Jones Bryn, Langford Paul R, Kroll J Simon, Yu Jun

Abstract excerpt

Previously, the authors have shown that inactivation of Shigella flexneri yihE, a gene of unknown function upstream of dsbA, which encodes a periplasmic disulphide catalyst, results in a global change of gene expression. Among the severely down-regulated genes are galETKM, suggesting that the yihE mutant, Sh54, may inefficiently produce the UDP-glucose and UDP-galactose required for LPS synthesis. This paper...

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Identifiers

PMID: 15073317
DOI: 10.1099/mic.0.26840-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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The role of the Shigella flexneri yihE gene in LPS synthesis and virulence.PMID 15073317Read ↗

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