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Article

Multicopy icsA is able to suppress the virulence defect caused by the wzz(SF) mutation in Shigella flexneri.

FEMS microbiology letters - 25 Apr 2003

Morona Renato, Van Den Bosch Luisa

Abstract excerpt

The lipopolysaccharides (LPS) of Shigella flexneri are important for virulence and their O antigen (Oag) polysaccharide chains affect IcsA (VirG)-mediated actin-based motility (ABM) within mammalian cells. S. flexneri 2a 2457T has smooth LPS whose Oag chains have two modal lengths (short (S)-type and very long (VL)-type), and has IcsA predominantly located at one pole on its cell surface. A S. flexneri 2457T...

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PMID: 12725929
DOI: 10.1016/S0378-1097(03)00217-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Multicopy icsA is able to suppress the virulence defect caused by the wzz(SF) mutation in Shigella flexneri.PMID 12725929Read ↗

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