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Article

Relative proximity and orientation of helices 4 and 8 of the GLUT1 glucose transporter.

The Journal of biological chemistry - 18 Jun 2004

Alisio Arturo, Mueckler Mike

Abstract excerpt

A structure has been proposed for glucose transporter-1 (GLUT1) based upon homology modeling that is consistent with the results of numerous mutagenesis studies (Mueckler, M., and Makepeace, C. (2004) J. Biol. Chem. 279, 10494-10499). To further test and refine this model, the relative orientation and proximity of transmembrane helices 4 and 8 were analyzed by chemical crosslinking of di-cysteine mutants created...

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PMID: 15073187
DOI: 10.1074/jbc.M402303200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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