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Article

CYP17 and CYP19 genetic polymorphisms in endometrial cancer: association with intratumoral aromatase activity.

Cancer letters - 30 Apr 2004

Berstein Lev M, Imyanitov Evgeny N, Kovalevskij Anatolij Ju, Maximov Sergei Ja, Vasilyev Dmitry A, Buslov Konstantin G, Sokolenko Anna P, Iyevleva Aglaya G, Chekmariova Elena V, Thijssen Jos H H

Abstract excerpt

Excessive estrogenic influence is known to be associated with initiation/promotion of endometrial cancer (EC). Allelic polymorphisms of the genes involved in steroidogenesis/steroid metabolism may contribute to EC susceptibility. It is important to know endocrine mechanisms by which such susceptibility is acquired. Here, we compared CYP19 (aromatase) and CYP17 (17alpha-hydroxylase/17,20-lyase) gene polymorphisms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15072828
DOI: 10.1016/j.canlet.2004.01.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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