Article
CYP19 gene polymorphism in endometrial cancer patients.
Journal of cancer research and clinical oncology - 1 Feb 2001
Berstein L M, Imyanitov E N, Suspitsin E N, Grigoriev M Y, Sokolov E P, Togo A, Hanson K P, Poroshina T E, Vasiljev D A, Kovalevskij A Y, Gamajunova V B
Abstract excerpt
PURPOSE: Initiation/promotion of endometrial cancer is known to be associated with estrogenic influence. Therefore, it is possible that some allelic polymorphisms of the genes involved in steroidogenesis or steroid metabolism contribute to endometrial cancer susceptibility. METHODS: Here, we compared CYP19 (aromatase) gene polymorphism in 85 endometrial cancer patients and in 110 non-affected women. RESULTS: The...
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