Resolution and characterization of polymorphic DNA by SSCP and chemical cleavage methodologies.

doi:10.1269/jrr.33.supplement_95

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Article

Resolution and characterization of polymorphic DNA by SSCP and chemical cleavage methodologies.

Journal of radiation research - 1 Mar 1992

Yatagai F, Hachiya S, Hama Y, Gordon A J, Hanaoka F

Abstract excerpt

A variety of techniques have been developed to detect single-base changes for the two different purposes. One is the detection of mutational events without phenotypic selection, and another is the rapid and conventional identification of mutations such as the specific base changes related to acti...

Topics

Base Sequence
DNA, Bacterial
Escherichia coli
Molecular Sequence Data
Mutation
Polymorphism, Genetic

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