Article
Resolution and characterization of polymorphic DNA by SSCP and chemical cleavage methodologies.
Journal of radiation research - 1 Mar 1992
Yatagai F, Hachiya S, Hama Y, Gordon A J, Hanaoka F
Abstract excerpt
A variety of techniques have been developed to detect single-base changes for the two different purposes. One is the detection of mutational events without phenotypic selection, and another is the rapid and conventional identification of mutations such as the specific base changes related to activation of oncogene, genetic diseases, etc. In this study, the utility of the two methods, single strand conformation...
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