Article
Current methods of mutation detection.
Mutation research - 1 Jan 1993
Cotton R G
Abstract excerpt
Mutation detection is important in all areas of biology. Detection of unknown mutations can involve sequencing of kilobases of DNA, often in many patients. This has lead to the development of methods to screen DNA for mutations as well as methods to detect previously described mutations. This rev...
Topics
- Animals
- Base Composition
- Carbodiimides
- DNA Mutational Analysis
- Electrophoresis
- Humans
- Mutation
- Nucleic Acid Conformation
- Nucleic Acid Heteroduplexes
- Polymorphism, Genetic
- Ribonucleases
- Sequence Analysis