Enzymatic and chemical cleavage methods.

Abstract excerpt

Cleavage-based methods of mutation detection offer a simple and intuitive means to detect and in most cases locate mutations within DNA fragment sizes ranging from 500 to 1500 bases. Their main advantages as a presequencing screening technology when scanning for unknown mutations is the potential to increase throughput by multiplexing. Combined with lower reagent costs per sample, mutation scanning methods offer...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Endodeoxyribonucleases
• Share to Hydroxylamine
• Share to Mutation