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Article

Neurobeachin is essential for neuromuscular synaptic transmission.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 7 Apr 2004

Su Yuhua, Balice-Gordon Rita J, Hess Darren M, Landsman Douglas S, Minarcik Jeremy, Golden Jeffrey, Hurwitz Ivy, Liebhaber Stephen A, Cooke Nancy E

Abstract excerpt

We report a random disruption in the mouse genome that resulted in lethal paralysis in homozygous newborns. The disruption blocked expression of neurobeachin, a protein containing a BEACH (beige and Chediak-Higashi) domain implicated in synaptic vesicle trafficking and an AKAP (A-kinase anchor pr...

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Identifiers

PMID: 15071111
DOI: 10.1523/JNEUROSCI.4644-03.2004
PMCID: PMC6729756

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15071111-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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