Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Drosophila rugose is a functional homolog of mammalian Neurobeachin and affects synaptic architecture, brain morphology, and associative learning.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 24 Oct 2012

Volders Karolien, Scholz Sabrina, Slabbaert Jan R, Nagel Anja C, Verstreken Patrik, Creemers John W M, Callaerts Patrick, Schwärzel Martin

Abstract excerpt

Neurobeachin (Nbea) is implicated in vesicle trafficking in the regulatory secretory pathway, but details on its molecular function are currently unknown. We have used Drosophila melanogaster mutants for rugose (rg), the Drosophila homolog of Nbea, to further elucidate the function of this multidomain protein. Rg is expressed in a granular pattern reminiscent of the Golgi network in neuronal cell bodies and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to A Kinase Anchor Proteins
Share to Association Learning

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Adhesion Molecules, Neuronal

Share to Horseradish Peroxidase

Share to Neuromuscular Junction

Share to Odorants

Share to Olfactory Receptor Neurons

Share to Presynaptic Terminals

Source

Open in PubMed Open full text

Identifiers

PMID: 23100440
DOI: 10.1523/JNEUROSCI.6424-11.2012
PMCID: PMC6704825

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Drosophila rugose is a functional homolog of mammalian Neurobeachin and affects synaptic architecture, brain morphology, and associative learning.PMID 23100440Read ↗

Drosophila mutants of the autism candidate gene neurobeachin (rugose) exhibit neuro-developmental disorders, aberrant synaptic properties, altered locomotion, and impaired adult social behavior and activity patterns.Semantic proximity Read ↗

Neurobeachin is essential for neuromuscular synaptic transmission.Semantic proximity Read ↗

rugose (rg), a Drosophila A kinase anchor protein, is required for retinal pattern formation and interacts genetically with multiple signaling pathways.Semantic proximity Read ↗

Synaptic homeostasis is consolidated by the cell fate gene gooseberry, a Drosophila pax3/7 homolog.Semantic proximity Read ↗

Altered gene regulation and synaptic morphology in Drosophila learning and memory mutants.Semantic proximity Read ↗

Neurobeachin is required postsynaptically for electrical and chemical synapse formation.Semantic proximity Read ↗

ben Functions with scamp during synaptic transmission and long-term memory formation in Drosophila.Semantic proximity Read ↗

A zebrafish gephyrinb mutant distinguishes synaptic and enzymatic functions of Gephyrin.Semantic proximity Read ↗

Diversification of behavior and postsynaptic properties by netrin-G presynaptic adhesion family proteins.Semantic proximity Read ↗

Odor-guided behavior in Drosophila requires calreticulin.Semantic proximity Read ↗

Overelaborated synaptic architecture and reduced synaptomatrix glycosylation in a Drosophila classic galactosemia disease model.Semantic proximity Read ↗

A genetic screen in Drosophila uncovers a role for senseless-2 in surface glia in the peripheral nervous system to regulate CNS morphology.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.