Article
straightjacket is required for the synaptic stabilization of cacophony, a voltage-gated calcium channel alpha1 subunit.
The Journal of cell biology - 7 Apr 2008
Ly Cindy V, Yao Chi-Kuang, Verstreken Patrik, Ohyama Tomoko, Bellen Hugo J
Abstract excerpt
In a screen to identify genes involved in synaptic function, we isolated mutations in Drosophila melanogaster straightjacket (stj), an alpha(2)delta subunit of the voltage-gated calcium channel. stj mutant photoreceptors develop normal synaptic connections but display reduced "on-off" transients in electroretinogram recordings, indicating a failure to evoke postsynaptic responses and, thus, a defect in...
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