Article
Microsatellite polymorphism in the heme oxygenase-1 gene promoter and the risk of atrial fibrillation in Taiwanese.
PloS one - 1 Jan 2014
Hsu Lung-An, Yeh Yung-Hsin, Kuo Chi-Tai, Chen Ying-Hwa, Chang Gwo-Jyh, Tsai Feng-Chun, Chen Wei-Jan
Abstract excerpt
BACKGROUND: Atrial fibrillation (AF) is associated with increased oxidative stress. Emerging evidence suggests that heme oxygenase-1 (HO-1) is a potent antioxidant system against various oxidative stress-related diseases. The human HO-1 promoter has a GT-repeat length polymorphism that can determine the level of gene transcription. OBJECTIVE: The aim of this study is to assess the role of the GT-repeat...
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