Article
Grb10 prevents Nedd4-mediated vascular endothelial growth factor receptor-2 degradation.
The Journal of biological chemistry - 18 Jun 2004
Murdaca Joseph, Treins Caroline, Monthouël-Kartmann Marie-Noëlle, Pontier-Bres Rodolphe, Kumar Sharad, Van Obberghen Emmanuel, Giorgetti-Peraldi Sophie
Abstract excerpt
One of the cellular mechanisms used to prevent continuous and enhanced activation in response to growth factors is the internalization and degradation of their receptors. Little is known about the molecular mechanisms involved in vascular endothelial growth factor receptor-2 (VEGF-R2) degradation...
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