Article
Identification of five chromosomal regions involved in predisposition to melanoma by genome-wide scan in the MeLiM swine model.
International journal of cancer - 20 May 2004
Geffrotin Claudine, Crechet Françoise, Le Roy Pascale, Le Chalony Catherine, Leplat Jean-Jacques, Iannuccelli Nathalie, Barbosa Angela, Renard Christine, Gruand Joseph, Milan Denis, Horak Vratislav, Tricaud Yves, Bouet Stéphan, Franck Michel, Frelat Gérard, Vincent-Naulleau Silvia
Abstract excerpt
In human familial melanoma, 3 risk susceptibility genes are already known, CDKN2A, CDK4 and MC1R. However, various observations suggest that other melanoma susceptibility genes have not yet been identified. To search for new susceptibility loci, we used the MeLiM swine as an animal model of hered...
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