Article
Swine leukocyte antigen (SLA) diversity in Sinclair and Hanford swine.
Developmental and comparative immunology - 1 Mar 2010
Ho Chak-Sum, Martens Gregory W, Amoss Max S, Gomez-Raya Luis, Beattie Craig W, Smith Douglas M
Abstract excerpt
The swine leukocyte antigen (SLA) haplotype B is associated with increased penetrance of the tumor traits in Sinclair swine cutaneous melanoma (SSCM). We established a series of SinclairxHanford swine crosses to facilitate genetic mapping of the tumor-associated loci. In this study, the SLA diversity in the founding animals was characterized for effective selection of maximum tumor penetrance in the pedigrees....
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