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Article

KIT and melanoma predisposition in pigs: sequence variants and association analysis.

Animal genetics - 1 Jun 2014

Fernández-Rodríguez A, Estellé J, Blin A, Muñoz M, Créchet F, Demenais F, Vincent-Naulleau S, Bourneuf E

Abstract excerpt

KIT mutations have been detected in different cancer subtypes, including melanoma. The gene also has been extensively studied in farm animals for its prominent role in coat color. The present work aimed at detecting KIT variants in a porcine model of cutaneous melanoma, the melanoblastoma-bearing Libechov Minipig (MeLiM). By sequencing exons and intron borders, 36 SNPs and one indel were identified. Of 10 coding...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Proto-Oncogene Proteins c-kit

Share to Skin Neoplasms

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Source

Identifiers

PMID: 24628300
DOI: 10.1111/age.12136

Genes

KIT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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