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Article

CDKN2A region polymorphism and genetic susceptibility to melanoma in the melim swine model of familial melanoma.

International journal of cancer - 20 Feb 2003

Le Chalony Catherine, Renard Christine, Vincent-Naulleau Silvia, Crechet Françoise, Leplat Jean-Jacques, Tricaud Yves, Horak Vratislav, Gruand Joseph, Le Roy Pascale, Frelat Gérard, Geffrotin Claudine

Abstract excerpt

Some herds of miniature swine are genetically predisposed to cutaneous melanoma. To test if swine melanoma susceptibility could be linked to the CDKN2A gene, which is involved in a proportion of 9p21-linked human familial melanoma, we performed a genetic analysis of miniature pigs of the MeLiM strain. F(1) and backcross animals were generated by crossing 1 MeLiM boar with healthy Duroc sows. We isolated the swine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12494470
DOI: 10.1002/ijc.10871

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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