Article
Linkage disequilibrium in young genetically isolated Dutch population.
European journal of human genetics : EJHG - 1 Jul 2004
Aulchenko Yurii S, Heutink Peter, Mackay Ian, Bertoli-Avella Aida M, Pullen Jan, Vaessen Norbert, Rademaker Tessa A M, Sandkuijl Lodewijk A, Cardon Lon, Oostra Ben, van Duijn Cornelia M
Abstract excerpt
The design and feasibility of genetic studies of complex diseases are critically dependent on the extent and distribution of linkage disequilibrium (LD) across the genome and between different populations. We have examined genomewide and region-specific LD in a young genetically isolated population identified in the Netherlands by genotyping approximately 800 Short Tandem Repeat markers distributed genomewide...
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