Article
Linkage disequilibrium and demographic history of the isolated population of the Faroe Islands.
European journal of human genetics : EJHG - 1 Jun 2002
Jorgensen Tove H, Degn Birte, Wang August G, Vang Maria, Gurling Hugh, Kalsi Gursharan, McQuillin Andrew, Kruse Torben A, Mors Ole, Ewald Henrik
Abstract excerpt
The isolated population of the Faroe Islands has a history of recent expansion after being limited to a small size for centuries. Such an isolated population may be ideal for linkage disequilibrium mapping of disease genes if linkage disequilibrium (LD) extends over large regions. Analyses of 18 markers on 12q24.3, spanning a region of 4.3 Mb (16 cM), revealed extensive LD in the Faroese population. Maximum LD...
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