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The interval of linkage disequilibrium (LD) detected with microsatellite and SNP markers in chromosomes of Finnish populations with different histories.

Human molecular genetics - 1 Jan 2003

Varilo Teppo, Paunio Tiina, Parker Alex, Perola Markus, Meyer Joanne, Terwilliger Joseph D, Peltonen Leena

Abstract excerpt

Linkage disequilibrium (LD) has been an efficient tool for fine mapping of monogenic disease genes in population isolates. Its usefulness for identification of predisposing loci for common, polygenic diseases has been challenged on the basis of anticipated allelic and locus heterogeneity. We compared the extent of LD among marker loci in Finnish subpopulations with divergent but well-characterized histories. One...

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PMID: 12490532
DOI: 10.1093/hmg/ddg005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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