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Article

Decay of linkage disequilibrium within genes across HGDP-CEPH human samples: most population isolates do not show increased LD.

BMC genomics - 28 Jul 2009

Bosch Elena, Laayouni Hafid, Morcillo-Suarez Carlos, Casals Ferran, Moreno-Estrada Andrés, Ferrer-Admetlla Anna, Gardner Michelle, Rosa Araceli, Navarro Arcadi, Comas David, Graffelman Jan, Calafell Francesc, Bertranpetit Jaume

Abstract excerpt

BACKGROUND: It is well known that the pattern of linkage disequilibrium varies between human populations, with remarkable geographical stratification. Indirect association studies routinely exploit linkage disequilibrium around genes, particularly in isolated populations where it is assumed to be higher. Here, we explore both the amount and the decay of linkage disequilibrium with physical distance along 211 gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19638193
DOI: 10.1186/1471-2164-10-338
PMCID: PMC2723139

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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