Article
Kinetics of asparaginase II fermentation in Saccharomyces cerevisiae ure2dal80 mutant: effect of nitrogen nutrition and pH.
Applied biochemistry and biotechnology - 1 Jan 2004
Ferrara Maria Antonieta, Mattoso Josiane M V, Bon Elba P S, Pereira Nei
Abstract excerpt
Although the quality of nitrogen source affects fermentation product formation, it has been managed empirically, to a large extent, in industrial scale. Laboratory-scale experiments successfully use the high-cost proline as a nonrepressive source. We evaluated urea as a substitute for proline in Saccharomyces cerevisiae ure2dal80 fermentations for asparaginase II production as a model system for...
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