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Article

Mks1p is a regulator of nitrogen catabolism upstream of Ure2p in Saccharomyces cerevisiae.

Genetics - 1 Oct 1999

Edskes H K, Hanover J A, Wickner R B

Abstract excerpt

The supply of nitrogen regulates yeast genes affecting nitrogen catabolism, pseudohyphal growth, and meiotic sporulation. Ure2p of Saccharomyces cerevisiae is a negative regulator of nitrogen catabolism that inhibits Gln3p, a positive regulator of DAL5, and other genes of nitrogen assimilation. Dal5p, the allantoate permease, allows ureidosuccinate uptake (Usa(+)) when cells grow on a poor nitrogen source such as...

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Identifiers

PMID: 10511541
DOI: 10.1093/genetics/153.2.585
PMCID: PMC1460790

Genes

MKS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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