Article
Immunogenicity of the histidine-to-tyrosine staphylococcal enterotoxin B mutant protein in C3H/HeJ mice.
Toxicon : official journal of the International Society on Toxinology - 15 Mar 2004
Savransky Vladimir, Pinelis Dmitriy, Korolev Sergey, Ionin Boris, Fegeding Konstantin
Abstract excerpt
Staphylococcal enterotoxin B (SEB) is a common cause of food poisoning and toxic shock. A safe and effective vaccine is needed to protect against the superantigenic effects of this toxin. We previously constructed and produced an apparently nontoxic SEB mutant having four histidine-to-tyrosine su...
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