Staphylococcal enterotoxin B mutants (N23K and F44S): biological effects and vaccine potential in a mouse model.

doi:10.1016/s0264-410x(96)00166-1

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Article

Staphylococcal enterotoxin B mutants (N23K and F44S): biological effects and vaccine potential in a mouse model.

Vaccine - 1 Feb 1997

Woody M A, Krakauer T, Stiles B G

Abstract excerpt

Superantigens produced by Staphylococcus aureus can cause food poisoning and toxic shock syndrome. The biological activities and vaccine potential of mutant staphylococcal enterotoxin B (SEB) proteins, N23K and F44S, were studied in a lipopolysaccharide-potentiated mouse model. Although 10 microg...

Topics

Animals
Antibodies, Bacterial
Cytokines
Enterotoxins
Lymphocyte Activation
Mice
Mice, Inbred BALB C
Mutation
Staphylococcal Infections
Staphylococcal Vaccines
Staphylococcus aureus
Superantigens
T-Lymphocytes

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