Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluation of a recombinant double mutant of staphylococcal enterotoxin B (SEB-H32Q/K173E) with enhanced antitumor activity effects and decreased pyrexia.

PloS one - 1 Jan 2013

Gu Liwei, Yue Junjie, Zheng Yuling, Zheng Xin, Wang Jun, Wang Yanzi, Li Jianchun, Jiang Yongqiang, Jiang Hua

Abstract excerpt

BACKGROUND: Immunotherapy has been used to improve patient immune function, inhibit tumor growth and has become a highly promising method of cancer treatment. Highly agglutinative staphylococcin (HAS), a mixture of Staphylococcus aureus culture filtrates, which include staphylococcal enterotoxin (SE) C as the active ingredient, has been used clinically as an immunomodifier in the treatment of a number of tumors...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytotoxicity, Immunologic
Share to Enterotoxins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, MHC Class II

Share to Immunotherapy

Share to Mice, Inbred NOD

Share to Mice, SCID

Share to Receptors, Antigen, T-Cell

Source

Open in PubMed Open full text

Identifiers

PMID: 23405232
DOI: 10.1371/journal.pone.0055892
PMCID: PMC3566101

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluation of a recombinant double mutant of staphylococcal enterotoxin B (SEB-H32Q/K173E) with enhanced antitumor activity effects and decreased pyrexia.PMID 23405232Read ↗

Enhancement of antitumor response of staphylococcal enterotoxin C2 mutant 2M-118 by promoting cell-mediated antitumor immunity.Semantic proximity Read ↗

Up-regulation of granzyme B and perforin by staphylococcal enterotoxin C2 mutant induces enhanced cytotoxicity in Hepa1-6 cells.Semantic proximity Read ↗

T-cell proliferation and antitumour activities of a truncated mutant of staphylococcal enterotoxin C2 with decreased cytokine secretion.Semantic proximity Read ↗

The staphylococcal enterotoxin (SE) familySemantic proximity Read ↗

Staphylococcus aureus isolates encode variant staphylococcal enterotoxin B proteins that are diverse in superantigenicity and lethality.Semantic proximity Read ↗

Putative staphylococcal enterotoxin possesses two common structural motifs for MHC-II bindingSemantic proximity Read ↗

In vivo and in vitro antitumor effects of a staphylococcal enterotoxin A mutant (SEA-H61D).Semantic proximity Read ↗

Staphylococcal enterotoxin microbial superantigensSemantic proximity Read ↗

Improved stability and yield of Fv targeted superantigen by introducing both linker and disulfide bond into the targeting moiety.Semantic proximity Read ↗

Structure of the staphylococcal enterotoxin B vaccine candidate S19 showing eliminated superantigen activity.Semantic proximity Read ↗

Induction of CD4+ regulatory T cells by stimulation with Staphylococcal Enterotoxin C2 through different signaling pathways.Semantic proximity Read ↗

Immunogenicity of the histidine-to-tyrosine staphylococcal enterotoxin B mutant protein in C3H/HeJ mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.