Article
The domain structure and functional relationships in the bacterial superantigen, SEB.
Biological chemistry Hoppe-Seyler - 1 May 1995
Hayball J D, O'Hehir R E, Lamb J R, Lake R A
Abstract excerpt
Staphylococcal enterotoxin B (SEB) has three essential biological properties that appear to be mediated by particular domains of the protein. As a superantigen, SEB triggers the T cell receptor (TcR) of a selected subset of T cells where the beta chain is encoded by particular V beta gene product...
Topics
- Amino Acid Sequence
- Base Sequence
- Blotting, Southern
- Enterotoxins
- Histocompatibility Antigens Class II
- Humans
- Lymphocyte Activation
- Molecular Sequence Data
- Mutation
- Receptors, Antigen, T-Cell
- Staphylococcus aureus
- Superantigens
