Article
Microsatellite instability in in vitro ageing of T lymphocyte clones.
Experimental gerontology - 1 Apr 2004
Neri Simona, Cattini Luca, Facchini Andrea, Pawelec Graham, Mariani Erminia
Abstract excerpt
Repair of mismatches in mammalian cell DNA is mediated by a complex of proteins that constitute the so-called mismatch repair system (MMR), the main post-replicative pathway for the correction of replication errors. Loss of MMR (as exemplified by germline mutations in some MMR genes, leading to h...
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