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Article

Microsatellite instability in in vitro ageing of T lymphocyte clones.

Experimental gerontology - 1 Apr 2004

Neri Simona, Cattini Luca, Facchini Andrea, Pawelec Graham, Mariani Erminia

Abstract excerpt

Repair of mismatches in mammalian cell DNA is mediated by a complex of proteins that constitute the so-called mismatch repair system (MMR), the main post-replicative pathway for the correction of replication errors. Loss of MMR (as exemplified by germline mutations in some MMR genes, leading to hereditary non-polyposis colorectal cancer) results in increased mutation rates at both coding sequences and in...

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Identifiers

PMID: 15050283
DOI: 10.1016/j.exger.2003.11.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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