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Article

An investigation of mutation as a function of age in humans.

Mutation research - 1 Aug 1994

King C M, Gillespie E S, McKenna P G, Barnett Y A

Abstract excerpt

An accumulation of mutations on their own or together with other age-related changes may contribute to aging and the development of age-related pathologies. The aim of this investigation was to assess the extent of DNA mutations as a function of age in humans. The mutant frequency (MF) at the hypoxanthine-guanine phosphoribosyl-transferase (hgprt) locus was assessed in lymphocytes isolated from male volunteers in...

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Identifiers

PMID: 7521005
DOI: 10.1016/0921-8734(94)90010-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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