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Article

Tetra- and pentanucleotide short tandem repeat instability in gastric cancer.

Electrophoresis - 1 Aug 1997

Silva F, Gusmão L, Alves C, Seruca R, David L, Amorim A

Abstract excerpt

The association between genetic instability in repetitive DNA domains and cancer has been reported in different types of malignancies. In this work we perform a comparative study of 29 gastric tumors with paired normal tissue using seven tetra-(FES/FPS, VWA31/A, HTPO, TH01, MBPB) and pentanucleotide (CD4, TP53) STR polymorphic markers regarding loss of heterozygosity and replication error status. Furthermore, we...

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PMID: 9378135
DOI: 10.1002/elps.1150180926

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FES

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