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Article

Novel dominant-negative mutation within the six domain of the conserved eye specification gene sine oculis inhibits eye development in Drosophila.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Mar 2005

Roederer Kristin, Cozy Loralyn, Anderson Jason, Kumar Justin P

Abstract excerpt

The development of the compound eye of Drosophila is controlled, in part, by the concerted actions of several nuclear proteins that form an intricate regulatory system. One member of this network is sine oculis (so), the founding member of the Six gene family. Mutations within so affect the entire visual system, including the compound eye. The vertebrate homologs Six3 and Six6 also appear to play crucial roles in...

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Identifiers

PMID: 15704100
DOI: 10.1002/dvdy.20316
PMCID: PMC2737192

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Novel dominant-negative mutation within the six domain of the conserved eye specification gene sine oculis inhibits eye development in Drosophila.PMID 15704100Read ↗

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