Article
The role of yan in mediating the choice between cell division and differentiation.
Development (Cambridge, England) - 1 Dec 1995
Rogge R, Green P J, Urano J, Horn-Saban S, Mlodzik M, Shilo B Z, Hartenstein V, Banerjee U
Abstract excerpt
An allele of the yan locus was isolated as an enhancer of the Ellipse mutation of the Drosophila epidermal growth factor receptor (Egfr) gene. This yan allele is an embryonic lethal and also fails to complement the lethality of anterior open (aop) mutations. Phenotypic and complementation analysis revealed that aop is allelic to yan and genetically the lethal alleles act as null mutations for the yan gene....
Topics
- Alleles
- Animals
- Cell Differentiation
- Cell Division
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- Embryonic Induction
- ErbB Receptors
- Eye
- Eye Proteins
- Genes, Lethal
- Microscopy, Electron, Scanning
- Phenotype