Article
Early-Transmitted Variants and Their Evolution in a HIV-1 Positive Couple: NGS and Phylogenetic Analyses.
Viruses - 19 Mar 2021
Lai Alessia, Giacomet Vania, Bergna Annalisa, Zuccotti Gian Vincenzo, Zehender Gianguglielmo, Clerici Mario, Trabattoni Daria, Fenizia Claudio
Abstract excerpt
We had access to both components of a couple who became infected with human immunodeficiency virus (HIV)-1 through sexual behavior during the early initial phase of infection and before initiation of therapy. We analyzed blood samples obtained at the time of diagnosis and after six months of combined antiretroviral therapy. Next-generation sequencing (NGS) and phylogenetic analyses were used to investigate the...
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