Article
Allelic polymorphism of TCRalpha chain constant domain genes in the bicolor damselfish.
Developmental and comparative immunology - 1 Jun 2004
Criscitiello Michael F, Kamper Sondra M, McKinney E Churchill
Abstract excerpt
T cell receptor (TCR) chains are composed of two extracellular domains, the membrane-distal variable domain and the membrane-proximal constant domain. Data presented here show that the TCRA 'constant' (C) domain of damselfish exhibits considerable allelic polymorphisms that appear to be positively selected. Each of 32 damselfish TCRAC clones showed different patterns of atypical polymorphism in the constant...
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