Article
Genetic diversity of the allodeterminant alr2 in Hydractinia symbiolongicarpus.
Molecular biology and evolution - 1 Feb 2011
Rosengarten Rafael D, Moreno Maria A, Lakkis Fadi G, Buss Leo W, Dellaporta Stephen L
Abstract excerpt
Hydractinia symbiolongicarpus, a colonial cnidarian (class Hydrozoa) epibiont on hermit crab shells, is well established as a model for genetic studies of allorecognition. Recently, two linked loci, allorecognition (alr) 1 and alr2, were identified by positional cloning and shown to be major determinants of histocompatibility. Both genes encode putative transmembrane proteins with hypervariable extracellular...
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