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Article

Interaction interface of human flap endonuclease-1 with its DNA substrates.

The Journal of biological chemistry - 4 Jun 2004

Qiu Junzhuan, Liu Ren, Chapados Brian R, Sherman Mark, Tainer John A, Shen Binghui

Abstract excerpt

Flap endonuclease-1 or FEN-1 is a structure-specific and multifunctional nuclease critical for DNA replication, repair, and recombination; however, its interaction with DNA substrates has not been fully understood. In the current study, we have defined the borders of the interaction between the F...

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Identifiers

PMID: 15037610
DOI: 10.1074/jbc.M401464200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15037610-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Interaction interface of human flap endonuclease-1 with its DNA substrates.PMID 15037610Read ↗

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