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Article

Interaction of helix D of elongation factor Tu with helices 4 and 5 of protein L7/12 on the ribosome.

Journal of molecular biology - 5 Mar 2004

Kothe Ute, Wieden Hans-Joachim, Mohr Dagmar, Rodnina Marina V

Abstract excerpt

Elongation factor Tu (EF-Tu) promotes binding of aminoacyl-tRNA to the A site of the ribosome. Here, we report the effects of mutations in helix D of EF-Tu and in the C-terminal domain of L7/12 on the kinetics of A-site binding. Reaction rates were measured by stopped-flow and quench-flow techniq...

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Share to Amino Acid Substitution
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Source

Identifiers

PMID: 15037065
DOI: 10.1016/j.jmb.2003.12.080

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15037065-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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