Article
Pol iota is a candidate for the mouse pulmonary adenoma resistance 2 locus, a major modifier of chemically induced lung neoplasia.
Cancer research - 15 Mar 2004
Wang Min, Devereux Theodora R, Vikis Haris G, McCulloch Scott D, Holliday Wanda, Anna Colleen, Wang Yian, Bebenek Katarzyna, Kunkel Thomas A, Guan Kunliang, You Ming
Abstract excerpt
In this study, we performed systematic candidate gene analyses of the Pulmonary adenoma resistance 2 locus. Differential gene expression in lung tissues and nucleotide polymorphisms in coding regions between A/J and BALB/cJ mice were examined using reverse transcription-PCR and direct sequencing. Although not all genes in the interval were analyzed at this moment due to the recent database updating, we have found...
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