Article
Molecular determinants of ER alpha and ER beta involved in selectivity of 16 alpha-iodo-7 beta estradiol.
The Journal of steroid biochemistry and molecular biology - 1 Jan 2004
Bhat Ramesh A, Stauffer Barbara, Unwalla Rayomand J, Xu Zhangbao, Harris Heather A, Komm Barry S
Abstract excerpt
The two known estrogen receptors, ER alpha and ER beta, are hormone inducible transcription factors that have distinct roles in regulating cell proliferation and differentiation. The natural ligand, 17 beta-estradiol (E2), binds with high affinity to both ER alpha and ER beta. However, a close an...
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