Article
Association between the interleukin-1beta C(-511)T polymorphism and blood pressure in a Chinese hypertensive population.
Immunology letters - 15 Feb 2004
Huang Guo, Niu Tianhua, Peng Shaojie, Ling Daijun, Liu Jing, Zhang Xuejun, Xu Xiping
Abstract excerpt
The interleukin-1beta (IL-1beta) is an important pro-inflammatory cytokine in a broad spectrum of physiological processes. Previous investigations have observed that levels of the IL-1beta were higher in essential hypertensive patients and the IL-1beta gene polymorphism has been shown to be related to IL-1 production. We hypothesized that genetically determined differences in activity or responsiveness of...
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