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Article

TGFB1 Functional Gene Polymorphisms (C-509T and T869C) in the Maternal Susceptibility to Pre-eclampsia in South Indian Women.

Scandinavian journal of immunology - 1 Oct 2015

Deepthi Goske, Chaithri Ponnaluri Kamakshi, Latha Prasanna, Rani Vital Usha, Rahman Police Fazul, Jahan Parveen

Abstract excerpt

Pre-eclampsia (PE), a pregnancy-specific vascular disorder characterized by hypertension and proteinuria, is hypothesized to be the result of inadequate placental angiogenesis with attendant systemic inflammation. The pleiotropic cytokine, Transforming Growth Factor-β1 (TGF-β1), is considered to be a key candidate gene in the molecular pathogenesis of PE by virtue of its ability to not only regulate angiogenesis...

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Source

Identifiers

PMID: 26173679
DOI: 10.1111/sji.12342

Genes

TGFB1
FOXP3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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