Article
Spliced human immunodeficiency virus type 1 RNA is reverse transcribed into cDNA within infected cells.
AIDS research and human retroviruses - 1 Feb 2004
Liang Chen, Hu Jing, Russell Rodney S, Kameoka Masanori, Wainberg Mark A
Abstract excerpt
Both the full-length and spliced RNA species of HIV-1 possess the necessary cis-acting elements including the primer binding site (PBS), the polypurine tract (PPT), as well as the 5' R and 3' R regions that are needed for their conversion to double-stranded cDNA through reverse transcription. Since measurable amounts of spliced viral RNA molecules can be detected within virus particles, we have examined the...
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