Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The 5' and 3' TAR elements of human immunodeficiency virus exert effects at several points in the virus life cycle.

Journal of virology - 1 Nov 1998

Das A T, Klaver B, Berkhout B

Abstract excerpt

The human immunodeficiency virus type 1 RNA genome contains a terminal repeat (R) sequence that encodes the TAR hairpin motif, which has been implicated in Tat-mediated activation of transcription. More recently, a variety of other functions have been proposed for this structured RNA element. To determine the replicative roles of the 5' and 3' TAR hairpins, we analyzed multiple steps in the life cycle of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cell Line
Share to Molecular Sequence Data

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to RNA, Messenger

Share to RNA, Viral

Share to Transcription, Genetic

Share to Transfection

Source

Open in PubMed Open full text

Identifiers

PMID: 9765469
DOI: 10.1128/JVI.72.11.9217-9223.1998
PMCID: PMC110341

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The 5' and 3' TAR elements of human immunodeficiency virus exert effects at several points in the virus life cycle.PMID 9765469Read ↗

The human immunodeficiency virus type 1 TAR RNA upper stem-loop plays distinct roles in reverse transcription and RNA packaging.Semantic proximity Read ↗

Genetic Dissociation of the Encapsidation and Reverse Transcription Functions in the 5′ R Region of Human Immunodeficiency Virus Type 1Semantic proximity Read ↗

Functional analysis of the complex trans-activating response element RNA structure in simian immunodeficiency virus.Semantic proximity Read ↗

Opening of the TAR hairpin in the HIV-1 genome causes aberrant RNA dimerization and packaging.Semantic proximity Read ↗

Human immunodeficiency virus type 1 TAR element revertant viruses define RNA structures required for efficient viral gene expression and replication.Semantic proximity Read ↗

Sequences in the 5' and 3' R elements of human immunodeficiency virus type 1 critical for efficient reverse transcription.Semantic proximity Read ↗

An Intact TAR Element and Cytoplasmic Localization Are Necessary for Efficient Packaging of Human Immunodeficiency Virus Type 1 Genomic RNASemantic proximity Read ↗

Molecular biology of the human immunodeficiency virus type 1Semantic proximity Read ↗

Different effects of the TAR structure on HIV-1 and HIV-2 genomic RNA translationSemantic proximity Read ↗

The Structure of the Human Immunodeficiency Virus Type-1 TAR RNA Reveals Principles of RNA Recognition by Tat ProteinSemantic proximity Read ↗

RNA structure and packaging signals in the 5' leader region of the human immunodeficiency virus type 1 genome.Semantic proximity Read ↗

Destabilization of the TAR hairpin leads to extension of the polyA hairpin and inhibition of HIV-1 polyadenylationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.