The 5' and 3' TAR elements of human immunodeficiency virus exert effects at several points in the virus life cycle.

doi:10.1128/JVI.72.11.9217-9223.1998

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Article

The 5' and 3' TAR elements of human immunodeficiency virus exert effects at several points in the virus life cycle.

Journal of virology - 1 Nov 1998

Das A T, Klaver B, Berkhout B

Abstract excerpt

The human immunodeficiency virus type 1 RNA genome contains a terminal repeat (R) sequence that encodes the TAR hairpin motif, which has been implicated in Tat-mediated activation of transcription. More recently, a variety of other functions have been proposed for this structured RNA element. To...

Topics

Base Sequence
Cell Line
Drug Stability
HIV Long Terminal Repeat
HIV-1
Humans
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
Protein Biosynthesis
RNA, Messenger
RNA, Viral
Transcription, Genetic
Transfection

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